Abstract:
Background:
Cancer outcomes in regional Victoria remain suboptimal compared to metropolitan areas, partly due to limited access to clinical trials and research infrastructure. Gippsland, a geographically and socioeconomically diverse region, has historically lacked a coordinated approach to cancer research. Recognising this gap, Latrobe Regional Health initiated a roadmap in early 2023 to establish a sustainable and regionally responsive cancer research program.
Roadmap – First Year:
The first year focused on building foundational governance, stakeholder engagement, and integration of research into clinical pathways. A dedicated cancer research lead was appointed, and partnerships were established with cooperative research groups such as TOGA, ANZUP, and BCT. Research priorities were identified based on local tumour stream burden, workforce capacity, and feasibility. Integration with multidisciplinary meetings facilitated early identification of eligible patients, while administrative systems were adapted to support trial activation and data management in a regional context.
Trial Activity and Recruitment:
Between February 2023 and February 2024, nine investigator-initiated and industry-sponsored trials were activated across tumour streams including breast, genitourinary, lung, and gastrointestinal cancers. A total of 41 patients were successfully recruited, with high engagement from breast and prostate cancer cohorts. These results reflect the growing acceptance of research as part of standard oncology care in the region.
Challenges and Barriers:
Key challenges included limited research-dedicated staff, delays in ethics and governance approvals, workforce turnover, and competing clinical priorities. Geographic spread and transport barriers also limited equitable trial access. Precision oncology and genomic integration remain underutilised due to logistical and funding limitations.
Future Directions:
Next steps include expanding trial portfolios, strengthening workforce capacity through dedicated research roles, improving access through teletrials, and embedding research education locally. The long-term vision is to create a research-active culture that ensures equitable trial access for all cancer patients in Gippsland.