Poster Presentation 2025 Joint Meeting of the COSA ASM and IPOS Congress

Patient-Reported Outcomes and Measures Applied in Individuals Undergoing Colonoscopy Surveillance for CRC: A Scoping Review   (126691)

Wudneh Belay 1 , Erin Symonds 1 2 , Melkalem Azanaw 1 , Meseret Molla 1 , Molla Wassie 1 , Geraldine Laven-Law 3 , Martha Menberu 1 , Muktar Ahmed 1 , Billingsley Kaambwa 1 , Norma Bulamu 1
  1. College of Medicine and Public Health, Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia
  2. Gastroenterology Department, Flinders Medical Centre, Southern Adelaide Local Health Network, Adelaide, SA, Australia
  3. The University of Adelaide, Adelaide, SA, Australia

Abstract  

Objectives/purpose: The aim of this scoping review was to summarise patient reported outcomes (PROs) and measures used in populations at elevated risk of colorectal cancer (CRC) undergoing regular colonoscopy surveillance.   

Sample and setting: The review included 89 empirical studies conducted worldwide.  

Procedures: Five databases were searched: Medline (OVID), Scopus, Web of Science, CINAHL, and PsycINFO (OVID). The review was limited to empirical, experimental, and observational studies published in English. Data extracted included the population characteristics, PROs assessed, measures used, risk factors, and assessment timepoints.     

Results: 7744 studies were screened, and 89 articles met the inclusion criteria. Eighteen different PROs and twelve different measures were identified. Abdominal discomfort (60.7%), pain (59.6%), nausea (57.3%), and headache (32.6%) were the most frequently reported PROs for cohorts undergoing surveillance colonoscopy. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire 30-item cancer specific (29.4%), Hospital Anxiety and Depression Scale (29.4%), Short Form-36 (29.4%), and EQ-5D-5L (29.4%) were the most frequently used measures. PROs were predominantly assessed after bowel preparation (before colonoscopy) (55.0%) and 1-2 days after colonoscopy (48.3%).

Conclusion and clinical implications: The findings from this scoping review provide valuable insights into the most important PROs and PROMs, identifying areas that require focused attention in clinical practice. This also underscore the variability in PROs and measures used for populations at elevated risk of CRC undergoing regular colonoscopy surveillance. This variability points to the need for standardisation of PRO assessment and the selection of the most suitable measures to improve the quality of care.