Poster Presentation 2025 Joint Meeting of the COSA ASM and IPOS Congress

Vocational adjustment in young adults with cancer (126797)

Rhonda Robert 1 , Clark R Andersen 1 , Kathleen M Murphy 2 , Sandra Medina-George 1 , Melissa Scardaville 2 , Sha-Ron Conley 1 , Michael Roth 1 , Vinh Nguyen 3 , Lex Frieden 4
  1. The University of Texas MD Anderson Cancer Center, Houston, TX, United States
  2. American Institutes for Research, Austin, TX, United States
  3. TIRR Memorial Hermann, Houston, TX, United States
  4. McWilliams School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, United States

Purpose. A high rate of workplace problems for young adults (YA) post-cancer diagnosis has been reported (Robert, R., et al., 2025). 

Methods. YA (18-39 years) vocational needs were evaluated across 1 year.  The YA Cancer Survivor Employment Needs survey & Patient-Reported Outcome Measurement Information System--Global Health, were administered online during initial vocational screening, 6- & 12-mos post.

Numeric/scaled variables were modeled by mixed effect linear models with relation to time point, blocking on patient to control for repeated measures correlation. Binary variables were similarly modeled by mixed-effect logistic regression. Within these models, change from baseline to each subsequent time point was assessed by contrasts with Dunnett-adjusted p-values. For discrete variables with more than two categories the change between baseline & each subsequent time point was assessed by Chi-square test with Hommel-adjusted p-values. All statistical tests assume an alpha of .05. 

Results. YAs were largely employed full-time, working 1 job. Degrees of comfort with cancer-related disclosures, satisfaction with work relationships, & expectations regarding career prospects ranged widely, yet remained steady.  

At 6 mos, most global health indicators reflected worsening (quality of life; physical/mental health; satisfaction w/social activities/roles), then rebounded to baseline at 12 mos.

Symptom interference with work attenuated significantly from baseline, at both 6 and 12 mos, with a few exceptions.  Concentration difficulty/interference w/work remained steady between baseline & 6 mos, then decreased in severity at 12 mos.  Mobility impairment/interference with work remained similar across time. 

Work productivity trended higher at 12 mos, compared with baseline & 6-mo. Fewer participants were taking unpaid, Family Medical Leave, or short-term disability leave at 6 & 12 mos.  Participants were increasingly familiar w/federal policies that support cancer-related accommodations at 6 & 12 mos.

Conclusion. YAs engaged in vocational screening & interventions maintained employment despite fluctuating health & symptom interference.