Background: Low-income and food-insecure cancer patients worldwide face cancer care inequities that result from economic, environmental, and social conditions. These factors limit access to cancer care and contribute to poorer experiences and outcomes. Effective interventions to improve access to cancer care are needed for these patients. Aim: To identify interventions and programs to improve access to cancer care for low-income and food-insecure cancer patients. Methods: We conducted a systematic review in accordance with PRISMA guidelines. We searched Medline, EMBASE, and CINAHL. Inclusion criteria: quantitative and qualitative studies published in English or French, describing interventions/programs to improve access to cancer care for low-income, poor, and/or food insecure cancer patients (18 years and over). Results: Our search identified 15,553 articles, of which 65 met the inclusion criteria. The quality of the selected studies was assessed using the JBI Critical Appraisal Tool and the Quality Assessment Tool for Quantitative Studies developed by the Effective Public Health Practice Project. Among the included studies, 55 interventions were conducted within the United States, with countries including Canada, France, Denmark, and Australia. Most interventions included financial support, educational programs, or various community-based approaches, such as patient navigation programs. The most promising studies came from randomized controlled trials, with those featuring social interventions involving patient navigation programs, survivorship nurse counseling, and community health initiatives. A notable example is the study “Randomized Controlled Trial of Survivorship Care Plans Among Low-Income, Predominantly Latina Breast Cancer Survivors” by Maley et al. (2017), which has a Strong ranking in both the JBI and Quality Assessment Tools. In conclusion, our presentation will help delineate effective interventions that can be scaled up nationwide to address poverty and its intersecting dimensions of equity.