Poster Presentation 2025 Joint Meeting of the COSA ASM and IPOS Congress

Anma therapy (Japanese massage) impacts the body, mind, and health-related quality of life in gynecologic cancer survivors: results from a randomized controlled trial and a case report (126046)

Nozomi Donoyama 1 , Toyomi Satoh 2 , Tetsutaro Hamano 3 , Nobuko Shiraiwa 1 4 , Daichi Kodama 5 , Ayumi Shikama 2
  1. Department of Health, Faculty of Health Sciences, Tsukuba University of Technology, Tsukuba, Ibaraki, Japan
  2. Department of Obstetrics and Gynecology, University of Tsukuba, Tsukuba, Ibaraki, Japan
  3. P4 Statistics Co. Ltd., Setagaya-ku, Tokyo, Japan
  4. Department of Neurology, Tsukuba University of Technology, Tsukuba, Ibaraki, Japan
  5. Department of Acupuncture and Moxibustion, Tsukuba University of Technology, Tsukuba, Ibaraki, Japan

Objectives: After medical treatment, cancer survivors often have physical and psychological symptoms that lower their health-related quality of life (HRQoL). Japanese Anma massage therapy (AMT) might help improve these situations; thus, we conducted a randomized controlled trial (RCT) and report the results and an illustrative case.

Sample and setting: Gynecologic cancer survivors, in a massage clinic division.

Procedures: In the RCT, 40 gynecologic cancer survivors were randomized to an AMT group that received 7 weekly 40-min AMT sessions and a no-AMT group. Changes in outcomes after an 8-week period were compared between the groups. The primary endpoint was severity of subjective physical symptoms assessed using a visual analogue scale (VAS). Secondary endpoints were HRQoL measured using the EORTC-QLQ-C30 and Profile of Mood States (POMS).

Results: In the primary analysis, the difference in the estimated least-squares means between the groups was -22.2 (95% CI, -34.4 to -10.1, p = 0.0007). For the secondary endpoints, significant improvements were seen in QLQ-C30 Global Health Status/QoL scores, fatigue and insomnia scores, and POMS scores for anger-hostility.

Care report: A 62-year-old woman had undergone surgery for clear cell carcinoma of the ovary, followed by 6 cycles of adjuvant chemotherapy. Due to peripheral neuropathy, pain and numbness appeared in the lower extremities and she became unable to wear shoes. After starting weekly 30-min AMT sessions, VAS scores for pain and numbness and the range of the affected area gradually decreased, and she could start wearing shoes made of soft materials. A nerve conduction study revealed that evoked action potentials had recovered and that nerve conduction velocities had improved. At follow-up after 3 years of AMT, recovery to within the normal range was observed in some areas on vibratory sense examination.

Conclusion and clinical implications: Continuing AMT improved various symptoms and HRQoL in gynecologic cancer survivors.