Oral Presentation 2025 Joint Meeting of the COSA ASM and IPOS Congress

Is  less more? Exploring consumer and clinician perspectives on deintensification in melanoma using digital democracy tools (126501)

Jennifer A Soon 1 2 3 , Fanny Franchini 2 , Peter Gourlay 4 5 , Phoebe Quinn 6 , Maarten J IJzerman 2 7 , Grant A McArthur 1 3 8
  1. Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
  2. Cancer Health Services Research, University of Melbourne, Melbourne, Victoria, Australia
  3. Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia
  4. Consumer Register, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
  5. Melanoma Research Victoria, Melbourne, Victoria, Australia
  6. Disaster, Climate & Adversity Unit, Melbourne School of Population and Global Health, University of Melbourne, Parkville, Victoria, Australia
  7. School of Health Policy and Management, Erasmus University, Rotterdam, The Netherlands
  8. Victorian Comprehensive Cancer Centre Alliance, Melbourne, Victoria, Australia

Background

Deintensification – reducing cancer treatment without compromising outcomes – can optimise survival and quality-of-life, reduce overtreatment, and improve healthcare resource utilisation. However, clinician and consumer attitudes towards deintensification in melanoma remains largely unknown. This study aimed to initiate dialogue using Pol.is, a digital democracy tool, augmented with demographic data and topic modelling (TM) to explore conversation subtopics.

Methods

Australians with lived experience of melanoma (LEM), their carers, and clinicians were invited to participate in the two-week online conversation. Demographics were collected via a linked Qualtrics survey. Pol.is seed statements were co-designed with a Consumer Working Group. Participants voted agree/disagree/unsure to statements and could contribute their own. Real-time feedback of opinion groups were generated through principal component analysis and k-means clustering. TM and linked analyses provided additional insights to opinion grouping and topics.

Results

There were ninety-eight participants from across Australia: 47 LEM, 41 clinicians, and 10 carers, with strong regional/remote representation (28%/5%). Two opinion groups emerged: Group A (GA), majority LEM, and Group B (GB), majority clinicians. GA voted consistently on statements balancing toxicity risk and efficacy and were less concerned about overtreatment (11% vs 70% GB). GB emphasised the need for better guidelines and evidence, and held a more utilitarian view towards resource usage within the healthcare system. TM revealed five topics: impact of insurance coverage on treatment, regionality and healthcare access, biomarker-guided approaches, dose attenuation, and general support for deintensification. Whilst the study did not reach statistical power, it exceeded the threshold for a meaningful Pol.is conversation (n=50).

Discussion & impact on practice

This study piloted a novel approach to consumer engagement in healthcare research that is easily scalable and may improve representation of diverse viewpoints. It highlighted areas of consensus and division between consumers and clinicians. Understanding these differences may facilitate effective implementation of deintensification strategies.